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Saved versus ray of exhaustion = Fatigue

A fatigued creature takes a -10% penalty to movement speed, -2 penalty to Strength and Dexterity, and cannot tumble. May be cured by the spells Heal, (Lesser)/(Greater) Restoration, or Panacea.

Fatigue may be the result of an enemy spell cast on the player such as Waves of Fatigue or Ray of Exhaustion (and you save versus it so only end up fatigued) but also occurs after the use of Barbarian Rage (not to be confused with friendly use of the Rage spell). You also receive fatigue if you cure Exhausted with Lesser Restoration.