Named chest loot

These specific items are found in chests in certain missions (generally, the same chest each time). Unlike unique quest rewards, they are not bound to the player who received it. Some of these items will only appear if a certain named monster is randomly spawned.

Particularly important items in the following lists include Muckbane, the Chill Shard, the Fragment of Silver Flame, the Silver Bow, the Planar Gird, and Chaosgarde, all of which provide capabilities that are impossible to find elsewhere. Other notable items are the Giant Stalker Knife, Bloodplate, and the Lightning Rod, which have powerful abilities rarely found on random items.

Korthos Island (explorer area)
Items drop from any of the 3 rare encounter chests, all bind on acquire.
 * Engraved Ring - Ring: Protection +1
 * Ring Of Alertness - Ring: Move Silently +3, Spot +1 (Considered a Starter Item, and may not be sold)

Necromancer's Doom
Drop point: in a chest behind a locked cell door, beyond Drusen d'Jorasco; all bind on acquire.
 * Arcane Gloves - Gloves: Spell Penetration I
 * Protective Gloves - Gloves: Shield 1/day
 * Runic Gloves - Gloves: +1 UMD

Sewer Rescue
Level 1 quest, no longer in the game.

Durk's Got A Secret
Level 2 quest

Garrison's Missing Pack
Level 2 quest

The Kobolds' New Ringleader
Level 2 quest

Retrieve the Stolen Goods
Level 2 quest

The Smuggler's Warehouse
Level 2 quest

Stealthy Repossession
Level 2 quest

Walk the Butcher's Path
Level 2 quest

The Crypt of Gerard Dryden
Level 3 quest

The Sacred Helm
Level 3 quest

The Swiped Signet
Level 3 quest

The Cloven-jaw Scourge: The Caverns of Shaagh
Level 4 quest

Irestone Inlet
Level 4 quest

Ghost of a Chance
Level 5 quest

Halls of Shan-To-Kor
Level 5 quest

Partycrashers
Level 5 quest

The Bloody Crypt
Level 6 quest

Redwillow's Ruins
Level 6 quest

The Grey Moon's Den: Extermination
Level 7 quest

Gwylan's Stand
Level 7 quest

The Pit
Level 7 quest

The Tear of Dhakaan
Level 7 quest

Caverns of Korromar
Level 8 quest

Stormcleave Outpost
Level 8 quest

The Xorian Cipher
Level 8 quest

The Church and the Cult
Level 9 quest

Haywire Foundry
Level 9 quest

The Shadow Crypt
Level 9 quest

Bring Me the Head of Ghola-Fan!
Level 10 quest

Hold for Reinforcements
Level 10 quest

Slavers of the Shrieking Mines
Level 10 quest

Tempest's Spine
Level 10 raid

Old Tempest's Spine Loot
These items have been replaced with improved versions and can no longer be found.
 * Enchanted Darkleaf Banded Armor - +1 Banded mail: Darkleaf,
 * Shining Adamantine Plate - +2 Full plate: Adamantine, Immunity to poison, Command
 * Mithral Breastplate of the Elements - +1 Breastplate: Mithral, ,
 * Cloak of Invisibility - Cloak:
 * Platemail of Giants - +2 Full plate: Damage reduction 5/- (End Chest)

Ran Spine 2/27/10 and found shining adamantine plate.

Ran Spine aug 2010 and found Enchanted Darkleaf Banded Armor.

An Offering of Blood
Level 11 quest

The Cursed Crypt
Level 11 quest

Dreams of Insanity
Level 11 quest

Sands of Menechtarun
Level 11 (8 - 15) Wilderness Adventure Area

Chains of Flame
Level 12 quest

The Chamber of Raiyum
Level 12 quest

Invaders!
Level 12 quest

The Twilight Forge
Level 12 raid

The Crucible
Level 14 quest

Desecrated Temple of Vol
Level 14 quest

Flesh Maker's Laboratory
Level 14 quest

Gianthold Tor
Level 14 quest

Ghosts of Perdition
Level 14 quest

Found in Madstone Quest inside Gianthold

Inferno of the Damned
Level 14 quest

Madstone Crater
Level 14 quest

The Prison of the Planes
Level 14 quest

Litany of the Dead
Level 15 quest

The Subterrane - Central
Level 16 (12-21) Wilderness Adventure Area, Raid

Skeleton Garamol chest

 * Dwarven Thrower
 * Flametongue
 * Frostbrand
 * Luck Blade
 * Mace of Smiting
 * Sun Blade
 * Icy Raiment

Prey on the Hunter
Level 17 quest

A New Invasion
Level 19 quest

Bastion of Power
Level 19 quest

Eye of the Titan
Level 19 quest

Genesis Point
Level 19 quest

Sins of Attrition
Level 19 quest

The Weapons Shipment
Level 19 quest

Unique Items with Non-Unique Locations
Items listed below don't have specific drop location and can drop from any level appropriate chest.
 * Boots of Speed- Boots:
 * Boots of Striding and Springing - Boots: +15% Striding,
 * Bottle of Air - Trinket: Underwater action
 * Brooch of Shielding - Trinket: Protects against Magic Missiles 50 charges
 * Circlet of Persuasion - Helm: Persuasion
 * Dark Blue Ioun Stone - Trinket: ,
 * Deep Red Ioun Stone - Trinket:
 * Disc of Lesser Acid Resistance - +2 Docent:
 * Dusty Rose Ioun Stone - Trinket: +1 Protection
 * Dwarven Thrower - +3 Throwing axe:, ,
 * Elemental Gem (Earth) - Equips to main hand:
 * Eyes of Charming - Goggles:
 * Flametongue - +1 Longsword: Flaming Burst
 * Frostbrand - +3 Greatsword: Frost,
 * Gauntlets of Ogre Power - Gloves: (Theres also  version which no longer drops)
 * Incandescent Blue Ioun Stone - Trinket:
 * Kargon's Tasty Ham - Heals 100 HP, Stuns you for 12 seconds
 * Keoghtom's Ointment - Trinket:
 * Luck Blade - +2 Shortsword:
 * Mace of Smiting - +3 Heavy mace: Adamantine, Smiting
 * Minor Circlet of Blasting - Helm,
 * Mithral Full Plate of Speed - +1 Full plate: Mithral,
 * Murlynd's Spoon - Trinket:
 * Necklace of Fireballs - Necklace:
 * Pale Green Ioun Stone (Pale Blue Ioun Stone) - Trinket:
 * Pale Lavender Ioun Stone - Trinket: Spell Absorption 40 Charges
 * Pearl of the Sirines - Trinket: Underwater action,
 * Pink Ioun Stone - Trinket:
 * Pink and Blue Ioun Stone - Trinket:
 * Plate Armor of the Deep - +1 Full plate: Underwater action,
 * Robe of the Magi - Robe: Magi
 * Restorative Gloves - Gloves: ,
 * Scarab of Protection - Trinket: ,
 * Scarab of Spell Absorption - Trinket: Absorbs up to 50 spell levels
 * Scarlet and Blue Ioun Stone - Trinket:
 * Stone of Good Luck - Trinket: Good luck
 * Sun Blade - +2 Shortsword (1d10 slashing damage): Flametouched Iron, +2 enhancement bonus vs Evil creatures, extra 1d10 + 4 damage vs. Undead
 * Swift Demise - +1 Heavy crossbow: Crippling
 * Vibrant Purple Ioun Stone -