Dust of Vile Darkness

Dust of Vile Darkness is a unique type of crafting ingredient used in the Esoteric Table and the Unholy Defiler of the Hidden Hand to upgrade items from Vecna Unleashed.

Only players with a copy of can loot the hidden chests containing the four types of dust. The chests each contain 0-3 dust on Casual difficulty, or 1-6 dust on all other difficulties, in addition to standard chest loot. Ransacked chests will not contain any dust. Each type of dust drops in a different quest:
 * and drop in Vecna Denied.
 * and drop in Taken in Hand.
 * and drop in The Evil We Know.
 * and drop in The Hand and the Eyes (note that this is in Grip of the Hidden Hand, not Vecna Unleashed.)

Raw ingredients