Harbinger of Madness

''Mysterious disappearances have the entire city on edge. Investigate the fates of the missing, dare to face hidden horrors that have broken the sanity of so many others, and destroy the monstrous perpetrator before it consumes your mind. Contains 4 hand-crafted adventures in the streets of Stormreach.'' (Level 15)

Story arc
Talk to Tessa Aster in the Harbor to pick up this quest chain. She will guide you through the story arc and reward you for completing all quests. You need to run the first three quests before you can start In the Flesh.

Reward list
The end reward (given by Tessa Aster) for completing all the quests is a mix of named items that can be pulled from optional chests in this chain, as well as several items gainable solely from here, and 1-2 items of random loot (BtA). You can talk to Tessa Aster and run the chain again - in any order - for another reward.

Following is the list of items that can only be acquired by completing the chain (except Beholder Plate Armor/Docent, those can drop from Opuloxx the Indomitable's chest in The Lord of Eyes).