Named quest rewards

Although most quest-givers allow you to select one item from a randomly-generated list of treasure items, certain multi-part quest chains have a fixed list of named, pregenerated items available. Almost all such items are Bind on Acquire (disallowing exchange between characters). You won't be able to choose freely between those, since all the quest-givers replace some of those items by random ones "of equal value".

Particularly useful (and popular) items in the following lists include: Black Widow Bracers, Graskitch's Skullcap, Puzzle Cap, Carniflex, Golden Cartouche, Iron Manacles, Linen Handwraps, Black Wolfskin Belt, Blademaster Gauntlets, Crimson Gemstone, Splinterskull Acolyte Ring, Mummified Bat, Jeweler's Loupe, Shrunken Head, Scavenged Warplate, Retribution, and Spectacular Optics. Almost any character will want several of those items as soon as they become available.

The Grotto
Level 1 quest

The Voyage (Veteran award quest)
Level 1 quest

Heyton's Rest
Level 1 quest

The Storehouse's Secret
Level 1 quest

The Cannith Crystal
Level 1 quest

The Collaborator
Level 1 quest

Redemption
Level 2 quest

Necromancer's Doom
Level 2 quest

Stopping the Sahuagin
Level 2 quest

Sacrifices
Level 2 quest

The Salvation of Korthos (Misery's Peak)
Level 3 quest

The Lost Seekers (aka "Waterworks")
Level 3-4 quests

Catacombs
Level 3-4 quests

The Seal of Shan-To-Kor
Level 3-5 quests

The Sharn Syndicate
Level 4 quests

Assault on Splinterskull (aka "Tangleroot")
Level 3-7 quests

Delera's Tomb and Return to Delera's Tomb
Level 5-8 quests

The Chronoscope
Level 6 quest

Cult of the Six
Level 8-10 quests

The Abandoned Excavation (aka "South Threnal")
Level 9-10 quests

Scarlet Scarab Powder
Combine 5 Scarabs from Litany of the Dead Part 1 quests into Scarlet Scarab Powder and turn it into Squire Rale in the Necropolis
 * Lumric's Longbow - +2 Longbow: Ghost Touch
 * Touch of the Silver Flame - Trinket: Lesser Undead Guard
 * Signal of the Silver Flame - Trinket: Lesser Turning

Dark Scarab Powder
Combine 5 Scarabs from Litany of the Dead Part 2 quests into Dark Scarab Powder and turn it into Squire Rale in the Necropolis
 * Morleth's Docent - +2 Docent:, Lesser Arcane Sigil (note this has no minimum level)
 * Righteous Bracers - Bracers: Lesser Undead Guard,
 * Signet of the Silver Flame - Ring: Lesser Undead Guard, ,

Eerie Scarab Powder
Combine 5 Scarabs from Litany of the Dead Part 3 quests into Eerie Scarab Powder and turn it into Squire Rale in the Necropolis
 * Beignin's Breath - Trinket: Exclusive,, Efficacy VI (CL:1, 3/day)
 * Dalorent's Seal - +3 Large Shield:, , Sacred, Lesser Turning
 * Ghostbane Longbow - +2 Longbow: Ghost Touch,
 * Kaelth's Touch - Trinket:, Faith (DR 5/evil)

The Spawn of Whisperdoom collectible
Level 11 quest

Invasion Tokens (Outsider Token collectible)
From Invaders!, level 12 quest

A Relic of a Sovereign Past (Adamantine Ore collectible)
Level 12 quest

Note: You are no longer limited to 1 NightForge item. You can continue to farm and get multiple items now.

Ancient Relic collectable
Items are all Minimum Level 10. Note that these Relic items are also required to advance The Reaver's Bane story arc.

Dragon Scales collectable
From Gianthold Tor, level 14 quest

Items are all minimum level 14, turn in 20 Scales to corresponding NPCs in Gianthold, to receive an armor of your choice.

Emerald Claw Nugget and Silver Flame Nugget
First of all, you must talk to the quest giver outside the Necropolis and get Silver Flame Trinket or Emerald Claw Trinket (you can only have one at a time), then bring it to the altar in the Bloody Crypt (of course the altar is guarded by a vampire boss). Then to the altar in the Shadow Crypt and the Cursed Crypt. Each time you use the altar, your necklace will be upgraded (however you only can use the altar once per instance). Then at last, you must turn it in to the altar in Ascension Chamber (Accursed Ascension raid). Talk to the quest giver for a choice of a final reward.

The Bloody Crypt
Level 6 quest
 * Emerald Claw Amulet - Necklace:, Cause Fear (3x/rest)
 * Silver Flame Amulet - Necklace: Negative Energy Absorption (1x/rest)

The Shadow Crypt
Level 9 quest
 * Emerald Claw Pendant - Necklace:, , Symbol of Fear (3x/rest)
 * Silver Flame Pendant - Necklace: Deathblock, Negative Energy Absorption (5x/rest)

The Cursed Crypt
Level 12 quest
 * Emerald Claw Talisman - Necklace: Fearsome,, , Symbol of Fear (3x/rest)
 * Silver Flame Talisman - Necklace: Deathblock, Continuous Protection from Evil, Negative Energy Absorption (10x/rest)